Chiara BrückPhD Candidate
Research groupEvaluation of screening
Chiara Brück pursues a PhD at the Department of Public Health at the Erasmus Medical Center. Her research focuses on the development of a microsimulation model for dementia in the Dutch population.
Microsimulation models can evaluate uncertainties, synthesize complex information, take trends in risk factors into account, and estimate long-term and population wide effects of (hypothetical) interventions. Based on the well‐known Microsimulation Screening Analysis (MISCAN) model from cancer research, Chiara is developing a dementia microsimulation model. MISCAN-Dementia can be used to predict how the burden of dementia will develop over the coming decades in terms of incidence, prevalence, mortality, costs, and quality of life.
Chiara has presented the MISCAN-Dementia model at the “Modelling Workshop Cross Comparison Challenge” for Alzheimer’s disease and dementia models organized by the IPECAD modelling group.
Chiara holds an MSc degree in Econometrics and Operations Research from the School of Business and Economics, Maastricht University.
Erasmus Medical Center Rotterdam
Internal post address Na-2401
P.O. Box 2040
3000 CA Rotterdam
Dr. Molewaterplein 40
3015 GD Rotterdam
In 2021, Chiara has joined the Academic Center of Excellence (ACE) – Alzheimer’s working group. The aim of the working group is to create a platform for all dementia researchers in ErasmusMC as well as organize meetings and guest lectures.
Chiara participated in the “Modelling Workshop Cross Comparison Challenge” for Alzheimer’s disease and dementia models organized by the IPECAD modelling group. The aim of the workshop was to increase the understanding of modelling methods in the area of Alzheimer’s disease and dementia, and to facilitate methodological development, transparency and comparability.
From 2020 to 2022, Chiara has been a member of the Junior Representative Committee (in Dutch: Junioren Vertegenwoordigersoverleg [JVO]). In her first year on the committee, she has held the Introduction role, which is responsible for helping new junior researchers find their way in the department. In her second year, she was the Chairwoman of the committee.
Most relevant publications
Projected prevalence and incidence of dementia accounting for secular trends and birth cohort effects: a population-based microsimulation study
European Journal of Epidemiology
Heterogeneity in Reports of Dementia Disease Duration and Severity: A Review of the Literature
Journal of Alzheimer's Disease
Letter to the Editor Regarding “Fluoxetine May Enhance VEGF, BDNF and Cognition in Patients with Vascular Cognitive Impairment No Dementia: An Open-Label Randomized Clinical Study”
Neuropsychiatric Disease and Treatment