Chiara Brück pursues a PhD at the Department of Public Health at the Erasmus Medical Center. Her research focuses on the development of a microsimulation model for dementia in the Dutch population.
Microsimulation models can evaluate uncertainties, synthesize complex information, take trends in risk factors into account, and estimate long-term and population wide effects of (hypothetical) interventions. Based on the well‐known Microsimulation Screening Analysis (MISCAN) model from cancer research, Chiara is developing a dementia microsimulation model. MISCAN-Dementia can be used to predict how the burden of dementia will develop over the coming decades in terms of incidence, prevalence, mortality, costs, and quality of life.
Chiara has presented the MISCAN-Dementia model at the “Modelling Workshop Cross Comparison Challenge” for Alzheimer’s disease and dementia models organized by the IPECAD modelling group.
Chiara holds an MSc degree in Econometrics and Operations Research from the School of Business and Economics, Maastricht University.
Erasmus Medical Center Rotterdam
Internal post address Na-2401
P.O. Box 2040
3000 CA Rotterdam
Visitor address:
Erasmus MC
Building: NA-23
Dr. Molewaterplein 40
3015 GD Rotterdam
- InterAct Beurs awarded by Alzheimer Nederland to support my research visit in fall 2022 to Harvard T.H. Chan School of Public Health, Center for Health Decision Science, Boston, MA, United States (€ 8,400)
- Travel grant awarded by Alzheimer Nederland to attend the Alzheimer’s Association International Conference (AAIC) 2022 in San Diego, CA, United States (€ 750)
In 2021, Chiara has joined the Academic Center of Excellence (ACE) – Alzheimer’s working group. The aim of the working group is to create a platform for all dementia researchers in ErasmusMC as well as organize meetings and guest lectures (i.e. ACE Alzheimer Day).
Chiara participated in the “Modelling Workshop Cross Comparison Challenge” for Alzheimer’s disease and dementia models organized by the IPECAD modelling group. The aim of the workshop was to increase the understanding of modelling methods in the area of Alzheimer’s disease and dementia, and to facilitate methodological development, transparency and comparability.
From 2020 to 2022, Chiara has been a member of the Junior Representative Committee (in Dutch: Junioren Vertegenwoordigersoverleg [JVO]). In her first year on the committee, she has held the Introduction role, which is responsible for helping new junior researchers find their way in the department. In her second year, she was the Chairwoman of the committee.
Publications list
Most relevant publications
Projections of costs and quality adjusted life years lost due to dementia from 2020-2050: a population-based microsimulation study
Alzheimer's & Dementia
Projected prevalence and incidence of dementia accounting for secular trends and birth cohort effects: a population-based microsimulation study
European Journal of Epidemiology
Cost-effectiveness Models for Alzheimer’s disease and related dementias: IPECAD Modelling Workshop Cross Comparison Challenge
Alzheimer's & Dementia
Heterogeneity in Reports of Dementia Disease Duration and Severity: A Review of the Literature
Journal of Alzheimer's Disease
Letter to the Editor Regarding “Fluoxetine May Enhance VEGF, BDNF and Cognition in Patients with Vascular Cognitive Impairment No Dementia: An Open-Label Randomized Clinical Study”
Neuropsychiatric Disease and Treatment
Onderzoekers Erasmus MC: komende jaren mogelijk veel minder dementiegevallen dan voorspeld
Online newspaper Nu.nl on June 23, 2022.
Onderzoekers Erasmus MC: komende jaren mogelijk veel minder dementiegevallen dan voorspeld
Newspaper AD (Algemeen Dagblad) on June 23, 2022.
Onderzoekers Erasmus MC: komende jaren mogelijk veel minder dementiegevallen dan voorspeld
Newspaper PZC (Provinciale Zeeuwse Courant) on June 23, 2022.
Dementia may not become as big a problem as thought
Amazing Erasmus MC on June 22, 2022.
Dementie mogelijk minder groot probleem dan gedacht
Amazing Erasmus MC on June 22, 2022.
Dementie is een hersenaandoening met veel impact op mensen en de maatschappij
Ouder Worden 2040 LinkedIn on June 29, 2022.