As a mathematical modeler, my research primarily focusses on modelling the natural-history of diseases and developing and evaluating methods for risk-stratification in screening based on individual characteristics. I currently do this within the U.S. National Cancer Institute’s CISNET consortium, the 4-IN-THE-LUNG-RUN consortium and through my VENI research project on developing dynamic risk-based screening policies.
Erasmus Medical Center Rotterdam
Internal post address Na-2401
P.O. Box 2040
3000 CA Rotterdam
Visitor address:
Erasmus MC
Room no.: NA-24th floor
Dr. Molewaterplein 40
3015 GD Rotterdam
My main research interests are:
- Decision-analytic modeling of healthcare strategies
- Risk-stratification
- Personalized screening
Most of my work is funded via the Dutch Research Council (personal Veni grant), the U.S. National Institute of Health/National Cancer Institute (CISNET Consortium), the European Union (4-IN-THE-LUNG RUN, Horizon 2020) and Cancer Research UK (SELECT).
Publications list
Most relevant publications
A Comparative Modeling Analysis of Risk-Based Lung Cancer Screening Strategies
Journal of the National Cancer Institute
Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial.
New England Journal of Medicine
Risk prediction models for selection of lung cancer screening candidates: A retrospective validation study.
PLOS Medicine
Performance and Cost-Effectiveness of Computed Tomography Lung Cancer Screening Scenarios in a Population-Based Setting: A Microsimulation Modeling Analysis in Ontario, Canada.
PLOS Medicine