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Luc E. Coffeng

Assistant Professor
Luc E. Coffeng

Research group

Infectious disease control
Luc E. Coffeng

Dr. Luc Coffeng is an Assistant Professor in Infectious Disease Control at the Department of Public Health of Erasmus MC, University Medical Center Rotterdam, The Netherlands. He has a mixed background as an MD, infectious disease epidemiologist, and mathematical modeller of transmission and control of infectious diseases. Dr. Coffeng works on the epidemiology and control of various neglected tropical diseases (NTDs) such as soil-transmitted helminths, filariases, visceral leishmaniasis, and is a principal investigator within the NTD Modelling Consortium. His work is primarily focused on informing public health policy and study design. He has held international Fellowship positions across the world, including at the University of Washington (Seattle, United States) to work on the NTD portfolio within the Global Burden of Disease Study, Australian National University (Canberra, Australia), The Kirby Institute at the University of New South Wales (Sydney, Australia), the Institute for Advanced Study (Amsterdam, The Netherlands), as well as a Distinguished Lorentz Fellowship at the Royal Netherlands Academy of Arts and Sciences. He further acts regularly as a consultant on applied statistics, modelling, and study design for several research groups around the world and has been an invited expert to several formal and informal WHO consultations on NTD control.

Erasmus MC, University Medical Center Rotterdam
Department of Public Health
P.O. Box 2040
3000 CA Rotterdam

My research and expertise can be broadly organised into three areas of activities:

  • Individual-based modelling of infectious diseases for public health policy and decision making in resource-constrained settings
  • Mathematical modelling of parasite kinetics in infected hosts
  • Applied Bayesian statistics

Most of my work is funded via NWO (Dutch Research Council, personal Veni grant), USAID, the Bill & Melinda Gates Foundation (NTD Modelling Consortium), NIHR, and the WHO. In addition, some of my work has been supported through Fellowships at the Institute for Health Metrics and Evaluation (Seattle, USA), the Australian National University (Canberra, Australia), and the Institute for Advanced Study (Amsterdam, Netherlands).

Publications list

Most relevant publications

A general framework to support cost-efficient fecal egg count methods and study design choices for large-scale STH deworming programs-monitoring of therapeutic drug efficacy as a case study.

Coffeng LE, Vlaminck J, Cools P, Denwood M, Albonico M, Ame SM, Ayana M, Dana D, Cringoli G, de Vlas SJ, Fenwick A, French M, Kazienga A, Keiser J, Knopp S, Leta G, Matoso LF, Maurelli MP, Montresor A, Mirams G, Mekonnen Z, Corrêa-Oliveira R, Pinto SA, Rinaldi L, Sayasone S, Steinmann P, Thomas E, Vercruysse J, Levecke B

PLoS Negl Trop Dis

Reducing societal impacts of SARS-CoV-2 interventions through subnational implementation

Dekker MM, Coffeng LE, Pijpers FP, Panja D, de Vlas SJ


Comparing antigenaemia- and microfilaraemia as criteria for stopping decisions in lymphatic filariasis elimination programmes in Africa

Stolk WA, Coffeng LE, Bolay FK, Eneanya OA, Fischer PU, Hollingsworth TD, Koudou BG, Méité A, Michael E, Prada JM, Caja Rivera RM, Sharma S, Touloupou P, Weil GJ, de Vlas SJ

PLoS Negl Trop Dis

Predicting epidemics and the impact of interventions in heterogeneous settings: standard SEIR models are too pessimistic

Coffeng LE, de Vlas SJ

J R Stat Soc Ser A Stat Soc 2022

Assessment of the required performance and the development of corresponding program decision rules for neglected tropical diseases diagnostic tests: Monitoring and evaluation of soil-transmitted helminthiasis control programs as a case study

Levecke B, Coffeng LE, Hanna C, Pullan RL, Gass KM

PLoS Negl Trop Dis

The burden of skin disease and eye disease due to onchocerciasis in countries formerly under the African Programme for Onchocerciasis Control mandate for 1990, 2020, and 2030

Vinkeles Melchers NVS, Stolk WA, van Loon W, Pedrique B, Bakker R, Murdoch ME, de Vlas SJ, Coffeng LE

PLoS Negl Trop Dis

Antibody and antigen prevalence as indicators of ongoing transmission or elimination of visceral leishmaniasis: a modelling study

Coffeng LE, Le Rutte EA, Munoz J, Adams E, de Vlas SJ

Clin Infect Dis

Survey design to monitor drug efficacy for the control of soil-transmitted helminthiasis and schistosomiasis

Coffeng LE, Levecke B, Hattendorf J, Walker M, Denwood MJ

Clin Infect Dis

News articles (selection)

Onderzoek: corona-aanpak had regionaler gekund. NRC, 7 March 2023.

Erasmus MC: ‘Scholensluiting tijdens coronacrisis in 2020 was achteraf gezien onnodig’. Regionale Publieke Omroep Rijnmond. 7 March 2023.

Steeds meer maatregelen in de prullenbak: hoelang is corona nog een pandemie?, 16 March 2022.

Een eind aan de maatregelen? Deze onderzoekers zien het niet snel gebeuren. NRC, 30 October 2020.

Doormodderen naar de volgende golf. NRC, 17 October 2020.

Is het virus eigenlijk al weg en andere dwarse ideeën over corona langs de wetenschappelijke meetlat. Volkskrant, 22 July 2020.

Het Duitse Jena stelde mondkapjes verplicht en zag de besmettingen flink dalen. Kwam dat door de kapjes? Volkskrant, 15 June 2020.

Welk land heeft de beste coronastrategie? Vijf lessen over de eerste coronagolf. Volkskrant, 22 May 2020.

Kabinet moet oppassen voor nieuwe golf op de IC’s, waarschuwen wetenschappers. Trouw 18 May 2020.

Welke maatregelen tegen corona kunnen worden versoepeld? (Handen wassen niet, zoveel lijkt zeker). Volkskrant, 21 April 2020.

Gebruik ons om de crisis te bezweren. NRC, 10 April 2020.

Oproep wetenschappers: creëer national platform voor coronaonderzoek. NRC, 10 April 2020.

Ik zag de eerste resultaten, en ik dacht: holy fuck, die tijdlijn. NRC, 6 April 2020.

Op1 (5 May 2020)

Late night talk show on Dutch national television: interview about what we can expect about the evolution of the Covid-19 pandemic.

EenVandaag (14 June 2020)

Daily news and backgrounds program on Dutch National Television: interview about what we can expect about the evolution of the Covid-19 pandemic.

Moeten jongeren zich ook laten vaccineren? (January 2021)

In deze vierdelige videoserie laat wetenschappers reageren op argumenten van mensen die twijfels hebben over het coronavaccin.